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Abstract:

Antipodally symmetric spherical functions play a pivotal role in diffusion MRI in representing sub-voxel-resolution microstructural information of the underlying tissue. This information is described by the geometry of the spherical function. In this paper we propose a method to automatically compute all the extrema of a spherical function. We then classify the extrema as maxima, minima and saddle-points to identify the maxima. We take advantage of the fact that a spherical function can be described equivalently in the spherical harmonic (SH) basis, in the symmetric tensor (ST) basis constrained to the sphere, and in the homogeneous polynomial (HP) basis constrained to the sphere. We extract the extrema of the spherical function by computing the stationary points of its constrained HP representation. Instead of using traditional optimization approaches, which are inherently local and require exhaustive search or re-initializations to locate multiple extrema, we use a novel polynomial system solver which analytically brackets all the extrema and refines them numerically, thus missing none and achieving high precision. To illustrate our approach we consider the Orientation Distribution Function (ODF). In diffusion MRI the ODF is a spherical function which represents a state-of-the-art reconstruction algorithm whose maxima are aligned with the dominant fiber bundles. It is, therefore, vital to correctly compute these maxima to detect the fiber bundle directions. To demonstrate the potential of the proposed polynomial approach we compute the extrema of the ODF to extract all its maxima. This polynomial approach is, however, not dependent on the ODF and the framework presented in this paper can be applied to any spherical function described in either the SH basis, ST basis or the HP basis.

BibTeX:
@article{gtmd-mia-13,
  hal_id =       {hal-00815120},
  url =          {http://hal.archives-ouvertes.fr/hal-00815120},
  title =        {{A polynomial approach for extracting the extrema of
                  a spherical function and its application in
                  diffusion MRI}},
  author =       {Ghosh, Aurobrata and Tsigaridas, Elias and Mourrain,
                  Bernard and Deriche, Rachid},
  abstract =     {{Antipodally symmetric spherical functions play a
                  pivotal role in diffusion MRI in representing
                  sub-voxel-resolution microstructural information of
                  the underlying tissue. This information is described
                  by the geometry of the spherical function. In this
                  paper we propose a method to automatically compute
                  all the extrema of a spherical function. We then
                  classify the extrema as maxima, minima and
                  saddle-points to identify the maxima. We take
                  advantage of the fact that a spherical function can
                  be described equivalently in the spherical harmonic
                  (SH) basis, in the symmetric tensor (ST) basis
                  constrained to the sphere, and in the homogeneous
                  polynomial (HP) basis constrained to the sphere. We
                  extract the extrema of the spherical function by
                  computing the stationary points of its constrained
                  HP representation. Instead of using traditional
                  optimization approaches, which are inherently local
                  and require exhaustive search or re-initializations
                  to locate multiple extrema, we use a novel
                  polynomial system solver which analytically brackets
                  all the extrema and refines them numerically, thus
                  missing none and achieving high precision. To
                  illustrate our approach we consider the Orientation
                  Distribution Function (ODF). In diffusion MRI the
                  ODF is a spherical function which represents a
                  state-of-the-art reconstruction algorithm whose
                  maxima are aligned with the dominant fiber
                  bundles. It is, therefore, vital to correctly
                  compute these maxima to detect the fiber bundle
                  directions. To demonstrate the potential of the
                  proposed polynomial approach we compute the extrema
                  of the ODF to extract all its maxima. This
                  polynomial approach is, however, not dependent on
                  the ODF and the framework presented in this paper
                  can be applied to any spherical function described
                  in either the SH basis, ST basis or the HP basis.}},
  keywords =     {* HARDI; * ODF; * Maxima; * Tensors; * Polynomials},
  language =     {English},
  affiliation =  {Athena - INRIA Sophia Antipolis , Laboratoire
                  d'Informatique de Paris 6 - LIP6 , POLSYS - INRIA
                  Paris-Rocquencourt , GALAAD - INRIA Sophia
                  Antipolis},
  pages =        {503--514},
  journal =      {Medical Image Analysis},
  volume =       17,
  number =       5,
  audience =     {international},
  year =         2013,
  month =        Jul,
}

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